http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103242827-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f90c1df3857ee72900e0015c75caecd9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f99335892b5acb9b7633287db8fc0117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2364361a7dd21c45d4dca6faa2926550 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3436f8134e14769ab0b16c94bb0c5d63 |
| publicationDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103242827-B |
| titleOfInvention | Florescent ion probe reagent for zinc ion detection and preparation method thereof |
| abstract | The invention discloses a florescent ion probe reagent for zinc ion detection, which contains triazole phenanthroline bridge type bis(beta-cyclodextrin), adopts phenanthroline as a probe molecule and takes the nitrogen atom on the phenanthroline ring and the nitrogen atom on the triazole ring as bonding sites of bivalent zinc ions. A preparation method comprises the following steps of: firstly synthesizing a 2,9-dipropargyl-1,10-phenanthroline intermediate from 2,9-dihydroxymethyl-1,10-phenanthroline, 3-propargyl bromide and the like; and then synthesizing a target product from the intermediate, uni-6-deoxy-6-azido-beta-cyclodextrin, sodium ascorbate and the like. As a water-soluble zinc ion florescent probe, the synthesis path of the cyclodextrin derivative is simple, the production cost is low, and the florescent ion probe reagent is suitable for amplification synthesis and practical production application; the zinc ion identifying operation is simple and practical and has high sensitivity, and the zinc ion is displayed by a fluorescence spectrum; and as a zinc ion florescent probe, the florescent ion probe reagent disclosed by the invention can effectively detect zinc ions in cells and has broad application prospects. |
| priorityDate | 2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.