http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103233017-B

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filingDate 2013-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6e9e044a38953fbe5f6d18112aad962
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_117ce9f135db11075304860d05d5aa92
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publicationDate 2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103233017-B
titleOfInvention Gametophyte antigen gam22 gene of Eimeria necatrix and application of gene
abstract The invention belongs to the field of genetic engineering vaccines, and in particular relates to a gametophyte antigen gene of chicken Eimeria necatrix, expression and application of an expression product of the gene. An open reading frame of the gene has the size of 561 bp. The gene is constructed into a prokaryotic expression vector pET28a-Engam22 to transform BL21 host bacteria to perform inducible expression. The expression product can be identified by chicken rehabilitation serum, and the fact shows that recombinant protein has immunogenicity. The recombinant eukaryotic expression plasmid pcDNA3.1-Engam22 constructed by the gene is used for immunizing chicks and can induce to generate humoral immunity and cellular immunity, and the fact shows that the gene can be applied to development of a chicken coccidiosis gene engineering vaccine.
priorityDate 2013-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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