abstract |
The invention discloses a kukoline structurally-reconstructed compound and a preparation method thereof. The kukoline structurally-reconstructed compound takes kukoline as a parent substance, and is a derivative which is prepared through a chemical synthesis method and contains new substituent groups on A, C and D rings or C and D rings. The kukoline structurally-reconstructed compound disclosed by the invention has certain activity in drug effect experiments on anti-inflammation, immunization, analgesia, anaphylactic reaction and the like. |