http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103232403-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D255-02 |
| filingDate | 2013-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103232403-B |
| titleOfInvention | A kind of preparation method of nitrogen heterocyclic |
| abstract | The invention discloses a kind of preparation method of nitrogen heterocyclic.It comprises the steps: (1) diethylenetriamine or triethylene tetramine and methylsulfonyl chloride react and generate Toluidrin; (2) Toluidrin with there is the compound of structure as Suo Shi chemical formula (a) in two phase reaction, and under 90 DEG C to reflux conditions, obtain Toluidrin nitrogen heterocyclic through benzyl triethyl ammonium amine compound and-5 composite catalyzing cyclizations of 15-hat; (3) Toluidrin nitrogen heterocyclic is carried out piptonychia alkylsulfonyl, then remake the process that methylates;n wherein, X represents bromine, iodine or sulphonate.Advantage of the present invention is: raw materials cost is low, and Atom economy is good, and safety simple to operate, is applicable to suitability for industrialized production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110922365-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110922365-A |
| priorityDate | 2013-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.