http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103230617-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-28
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-44
filingDate 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a019eafa6437822db2190887bb88d8d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94acecba7bf17caa8ed2b1e5473220b5
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publicationDate 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103230617-B
titleOfInvention Collagen/chitosan micro-nano fiber composite hemostatic membrane material and preparation method thereof
abstract The invention discloses a collagen/chitosan micro-nano fiber composite hemostatic membrane material and a preparation method thereof. The preparation method is characterized by comprising the following steps of: extracting a medical biological skin sheet serving as a raw material by an ultrasonic technology to prepare I type collagen; mixing hexafluoroisopropanol and acetic acid according to different volume ratios to prepare a spinning solvent; mixing the prepared I type collagen and chitosan in a certain mass ratio and adding the mixture into the spinning solvent; stirring in an ultrasonic cleaner at room temperature until the material is transparent to prepare electrostatic spinning mother liquid at the concentration of 4 to 10 percent; injecting the electrostatic spinning mother liquid into an electrostatic spinning machine and performing electrostatic spinning to obtain a collagen/chitosan micro-nano fiber composite membrane; soaking the collagen/chitosan micro-nano fiber composite membrane into natural biomacromolecules and Chinese herbal medicines sequentially; and freeze-drying to obtain the collagen/chitosan micro-nano fiber composite hemostatic membrane material. The collagen/chitosan micro-nano fiber composite hemostatic membrane material has excellent biocompatibility, biodegradability, adhesion property and the like, can quickly stop bleeding, resist inflammation, ease pain and promote wound healing, and can be applied to trauma hemostasis and repair and general civil hemostasis emergency treatment.
priorityDate 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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