http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103230617-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-44 |
filingDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a019eafa6437822db2190887bb88d8d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94acecba7bf17caa8ed2b1e5473220b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_815c62f08370dc4df43d2fc416ebf1af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5017c9224e448ae921f1c6eb736b7d41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45a5e8dc11bf105f7caa3a309a6595e |
publicationDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103230617-B |
titleOfInvention | Collagen/chitosan micro-nano fiber composite hemostatic membrane material and preparation method thereof |
abstract | The invention discloses a collagen/chitosan micro-nano fiber composite hemostatic membrane material and a preparation method thereof. The preparation method is characterized by comprising the following steps of: extracting a medical biological skin sheet serving as a raw material by an ultrasonic technology to prepare I type collagen; mixing hexafluoroisopropanol and acetic acid according to different volume ratios to prepare a spinning solvent; mixing the prepared I type collagen and chitosan in a certain mass ratio and adding the mixture into the spinning solvent; stirring in an ultrasonic cleaner at room temperature until the material is transparent to prepare electrostatic spinning mother liquid at the concentration of 4 to 10 percent; injecting the electrostatic spinning mother liquid into an electrostatic spinning machine and performing electrostatic spinning to obtain a collagen/chitosan micro-nano fiber composite membrane; soaking the collagen/chitosan micro-nano fiber composite membrane into natural biomacromolecules and Chinese herbal medicines sequentially; and freeze-drying to obtain the collagen/chitosan micro-nano fiber composite hemostatic membrane material. The collagen/chitosan micro-nano fiber composite hemostatic membrane material has excellent biocompatibility, biodegradability, adhesion property and the like, can quickly stop bleeding, resist inflammation, ease pain and promote wound healing, and can be applied to trauma hemostasis and repair and general civil hemostasis emergency treatment. |
priorityDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.