| abstract |
The invention relates to application of terfenadine in preparation of a zebra fish heart function damage model. The application comprises the following steps of putting normally developing zebra fish which is fertilized 2-3 days later into breeding water solution containing terfenadine, and cultivating for 24-48 hours at constant temperature of 28 DEG C to prepare the zebra fish heart function damage model. Terfenadine is utilized for the first time to build the zebra fish heart function damage model; the built zebra fish heart function damage model has the advantages that the zebra fish heart function damage model is simple and convenient to prepare, rapid, stable, reliable, and good in repeatability; the manufacturing cost of the heart function damage model is reduced; and the reliability of the experimental research result is improved. |