http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103224558-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 |
| filingDate | 2013-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103224558-B |
| titleOfInvention | A kind of preparation method of Exenatide |
| abstract | The present invention relates to a kind of preparation method of Exenatide.The method take aminoresin as raw material, first by aminoresin deprotection, then is connected with the amino acid of Fmoc protection in turn by the mode of coupling one by one, obtains Exenatide [3-39] peptide-resin of side chain full guard base, then the coupling R that uses the same methodn 1 -His (Rn 2 )-Gly-OH completes the connection of His-Gly two amino acid fragments.The inventive method is used for heavy industrialization and prepares Exenatide, and product purity is greater than 99.0%, Exenatide [D-Hisn 1 ] impurity, Exenatide [Des Glyn 2 ] impurity is all less than 0.1%. |
| priorityDate | 2013-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 218.