http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103223173-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2013-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34e5b23824afb79ba3804112e6f062ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_587ce8b5077be18c8fbd3273abedd591 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ddf828ff0b132886354b4ce6e794696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5212b1ed25bcd3a9cd9271bbf68de60c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a144db503d373f312faa33140ddcb2d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c81ba93a992a689656d4de7e69fc9085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1e58085222a25b9c124207c1714648c |
| publicationDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103223173-B |
| titleOfInvention | Capsule polyurethane drug controlled release body with temperature control switch, and preparation method thereof |
| abstract | The invention discloses a capsule polyurethane drug controlled release body with a temperature control switch. The capsule polyurethane drug controlled release body is prepared by loading the drug by a temperature-sensitive polyurethane capsule pipe. In the application of the capsule polyurethane drug controlled release body, a drug release characteristic with temperature response is expressed; and an 'open-close' effect is present. The capsule wall polyurethane molecules are in a rigid crystalline state below the switch temperature, so that diffusion and release of the drug in the controlled release body are blocked; when the temperature rises to higher than the switch temperature, the polyurethane molecules are in a molten state, so that the drug in the body migrates to the capsule wall and the capsule wall drug release outward continuously, with the concentration as a mass ladder force. Besides, the special design of the capsule wall can realize ideal drug diffusion capacity. The invention also discloses a preparation method of the capsule polyurethane drug controlled release body. The temperature-sensitive polyurethane capsule pipe of the drug controlled release body and unsymmetrical structure of the capsule wall design makes the drug controlled release body have fast temperature response speed, good repeatability of the drug release switch, freely adjustable drug release amount, capacity of uniform drug release, no physiological toxicity, so that the drug controlled release body has wide application prospects in clinic local drug treatment. |
| priorityDate | 2013-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.