http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103214420-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9dd36c71da228827462258497f2eb2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-68 |
| filingDate | 2013-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fe02334dbf9295709e951fd5b87b8e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da27c03b6333de7df5adca6221442f50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff29e0f0efbb79a79731226387d9bf34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50c7ab98d9a3467f5ce31da7a80ba7ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cea0c1b575a127c23aee2cb33d6479d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_569c85001db52236492450ce05039828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_619543d7d3cccfc0c93bd99f4aaaa235 |
| publicationDate | 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103214420-B |
| titleOfInvention | Method for preparing 2-butyl-4-chloro-5-formylimidazole |
| abstract | The invention relates to a method for preparing 2-butyl-4-chloro-5-formylimidazole and belongs to the technical field of pharmaceutical synthesis. The method for preparing 2-butyl-4-chloro-5-formylimidazole provided by the invention comprises the following steps of: performing condensation reaction of pentamidine hydrochloride with glyoxal and controlling the pH value of the system in the range of 6.0-7.5; after the reaction terminates, arousing dehydration reaction of the compound of formula III, thereby obtaining 2-butyl-1H-imidazole-5(4H)-ketone; and finally, reacting 2-butyl-1H-imidazole-5(4H)-ketone with N,N-dimethylformamide in the presence of phosphorus oxychloride, thereby obtaining 2-butyl-4-chloro-5-formylimidazole. The method provided by the invention is simple in process course, easy to operate, and high in purity of product and yield. |
| priorityDate | 2013-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.