| abstract |
The invention relates to compounds represented by a formula (I), and pharmaceutically acceptable salt, prodrug, and solvate thereof, wherein R1, R2, R3, R4, R5, and R6 are defined as in the specifications. The compounds are protein kinase inhibitors, and especially protein kinase Mek inhibitors. The compounds can be used in treating cancers and inflammations in mammals. The invention also discloses a preparation method of the compounds represented by the formula (I), and medicine compositions comprising the compounds. |