http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103191079-B

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filingDate 2013-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9651ac1e7b0dad1839973c7647959ffe
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publicationDate 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103191079-B
titleOfInvention Citicoline sodium tablet and preparation method thereof
abstract The invention provides a citicoline sodium tablet and a preparation method thereof. The citicoline sodium tablet provided by the invention contains citicoline sodium, starch, lactose, sodium carboxymethyl starch, 10% starch slurry and magnesium stearate. The prescription of a coating solution includes stomach-soluble coating powder and ethanol. The preparation method comprises the steps of: (1) preparation of an uncoated tablet: uniformly mixing main drugs with the lactose, grinding the mixture to pass through a 80-mesh sieve, respectively adding the starch and the sodium carboxymethyl starch and carrying out uniform mixing, passing through the 80-mesh sieve twice, adding the 10% starch slurry, adequately and uniformly mixing to prepare soft materials, carrying out pelletizing by utilizing a 20-mesh sieve, drying at 60 DEG C, adding the magnesium stearate, and carrying out uniform mixing, tabletting and testing; and (2) coating. The citicoline sodium tablet has the advantages of good stability, low cost, high active ingredient content and the like.
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