| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_052090cc7db56227ba0673783194227a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 |
| filingDate |
2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a79922c79907ee04161f9c6073bdd241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8809a5564bbb8ece60cbf564c836a6f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48c02b6647df8809a1a1a43e77ff0652 |
| publicationDate |
2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103183724-B |
| titleOfInvention |
Preparation method of docetaxel conjugate |
| abstract |
The invention discloses chemical synthesis as well as anti-tumor functions of bi-functional conjugates shown in Figure 1, and in particular relates to a conjugate formed by docetaxel and MDP ramification, and docetaxel and MDP simplifier (which is a potent immunopotentiator) are connected, so that dual effects of anti-tumor and anti-tumor metastasis combined with chemical treatment and immunological therapy are realized. The invention combines solid-phase synthesis with liquid-phase synthesis methods to synthesize a plurality of conjugates formed by docetaxel and MDP simplifier, and proves that the conjugates can be used for preparing anti-tumor medicine through reliable biological experimental methods and data. |
| priorityDate |
2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |