| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_254f925547e7afc311a1832cf37751ac |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a2f43ea07766ad3b254dba2046cc36c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42dddc03550ff80370b88930fdaea7a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf94e39ed5b1f1d30c93ecec3477675f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa1fb7c76540b4f2b214c0193001d824
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca6f7e736ad54cb736b95d5f7b704fb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b07e869806ad56b0a18fdd01666f7339
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_406671a693815ea2a9dae3aef769226c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b88c29f3395289732d30a5c617d441bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6092b92249ebb521d96b5da1d0a5e9ad |
| publicationDate |
2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103173529-B |
| titleOfInvention |
Associated use of human NLK (Neuroleukin) gene and associated medicines |
| abstract |
The invention discloses associated use of a human NLK (Neuroleukin) gene and associated medicines. The invention discloses use of NLK in tumor treatment, tumor diagnosis and medicine preparation. The invention further constructs separated oligonucleotide molecules capable of reducing NLK genetic expression in tumor cells, cells comprising separated oligonucleotide molecules and NLK gene interference lentivirus, and discloses use thereof. The separated oligonucleotide molecules capable of reducing NLK genetic expression in tumor cells or the NLK gene interference lentivirus provided by the invention can specifically inhibit expression of the human NLK gene, in particular lentivirus, and can efficiently infect target cells and inhibit expression of human NLK gene in the target cells so as to further inhibit growth of tumor cells and promote tumor apoptosis. The gene has significant meaning in tumor treatment. |
| priorityDate |
2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |