Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07707223721223ce27dfca225f7d9c30 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
filingDate |
2006-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85c4f9d4e16fa5d7ad3b5e530fad2551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dc2049de16ce63118b18d1531ddd23b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a1c354bcd85e95468860a5fedec2c7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa12eb3d993421253ba1095996429f39 |
publicationDate |
2013-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-103172747-A |
titleOfInvention |
Conjugates of biologically active proteins having a modified in vivo half-life |
abstract |
Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107743494-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107743494-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113480667-A |
priorityDate |
2005-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |