http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103172713-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9183688cf474caf7e736799dba212477 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-36 |
| filingDate | 2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3c71f6539ac1dc4f1f37b63a40c3c01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a0d0e5d832ad3c428e75301a2bf449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e606eadfef29ba56a17a3d99b3974c5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bde37a6e07e39c54da3470e83f8dc50d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc8b5385fb8bbe64420e707af1263bbb |
| publicationDate | 2015-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103172713-B |
| titleOfInvention | Streptavidin mutant and preparation method thereof |
| abstract | The invention discloses a streptavidin mutant and a preparation method thereof. The nucleotide sequence of the streptavidin mutant is represented by SEQ ID No.6 in the sequence table. The amino acid sequence of the mutant is represented by SEQ ID No.7 in the sequence table. The mutant comprises mutations of 5 amino acids, which are E14D, T42Y, Y43T, S52G, and R53D. The invention provides the streptavidin mutant and the preparation method thereof. With the streptavidin mutant SA122m5, the affinity with biotin derivatives such as 2-iminobiotin is improved, and biotinylated product detection is facilitated. Half-life period of the mutant combined with biotin is prolonged, such that experiments and image researches requiring long-time observation are facilitated. |
| priorityDate | 2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 198.