http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103172711-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5801cc46e2a55e642df5ef73f2dcbe8e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-50 |
filingDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fe24408b70baa28f67bd4362ed78f7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d3f0f74149418262b35aeec7c82b707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a24636d82831a70c6d0e921bc9513793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5a28c17f52e324b9151013c0d30d2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4159cc7d684359be3d0d392a1c6ca81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd3e1dd662a8cd38d1a038e24f5ac6ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d5c667708532533acfae1c46f20cb46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_841fc697ab21413cd4cc017cb9b97e7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95a9dba9f631bd2de15f6f1c5683e5a5 |
publicationDate | 2013-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103172711-A |
titleOfInvention | Expression and purification of amino terminal region of SARS coronavirus non-structural protein nsp2, and crystalline structure of amino terminal region |
abstract | The invention provides a crystalline three-dimensional structure of an amino terminal region of an SARS (severe acute respiratory syndrome) coronavirus non-structural protein nsp2. The amino terminal region of the SARS coronavirus non-structural protein nsp2 comprises amino acids at positions in a range of about 1-50 to about 150-300 of the SARS coronavirus non-structural protein nsp2; and atoms in the crystalline three-dimensional structure have at least 40% of atomic coordinates in a table 1, or the average root mean square deviation of the main-chain carbon-skeleton atomic structure coordinates of the at least 40% amino acids of the crystalline three-dimensional structure of the amino terminal region of the SARS coronavirus non-structural protein nsp2 and the coordinates in the table 1 is not greater than 1.5 angstroms. The invention also provides an expression, purification and crystallization method of the SARS coronavirus non-structural protein nsp2, the crystalline structure of the SARS coronavirus non-structural protein nsp2, and theoretic guiding meanings and applications of the crystalline structure in functional researches, latent drug screening and drug designs. |
priorityDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 512.