abstract |
The invention relates to a preparation and applications of a 1,4-disubstituted-1,2,3-triazole compound, and particularly provides a 1,4-disubstituted-1,2,3-triazole compound with a structure shown in the following general formula (I); the compound has a certain inhibitory effect on the growth of K562, KG1a, HCC-1954, the MCF-7 cells, and especially can effectively restrain the survival and growth of KG1a cells, wherein R1 and R2 are selected from H, F, Cl, Br, I, CH3O and CF3; and R3 is selected from CH3O. |