http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103159753-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 |
| filingDate | 2013-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103159753-B |
| titleOfInvention | 4,4 '-di-n-butyl-5,5 '-two (4-pyridyl)-2,2 '-double thiazole and method for making thereof and to the fluorescence sense of iron ion and biologic applications |
| abstract | A kind of 2,2 '-double thiazole compound, it is 4, and 4 '-normal-butyl-5,5 '-(4-pyridyl)-2,2 '-double thiazole, has following structural formula:n it is in alcohol-water mixing solutions, can selectivity chelating Fen 3+ , form a kind of fluorescence color and change sapphire scale fluorescence into from bluish voilet, Fluorescence Increasing about 100%.This Fluorescence Increasing is except Hgn 2+ ion is neither subject to alkalimetal ion (as Na outwardn + , Kn + ), be not subject to alkaline-earth metal ions (as Ca yetn 2+ , Mgn 2+ ) and most of transition metal ion (as Znn 2+ , Pbn 2+ , Agn + ) etc. impact.In addition, part and part-Fen 3+ complex compound (5-11) within the scope of larger pH keeps stable simultaneously, can detect Fe in redox environmentn 3+ / Fen 2+ change in concentration.The imaging experiment of Hela cell, Yeast cell and zebra fish fish-egg shows that 2Py2TZ has good cell permeability and low bio-toxicity, and can the iron ion of real-time mark trace, can be applied to iron ion sensor.The invention discloses its method for making. |
| priorityDate | 2013-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.