http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103156805-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b8f22aecbd06c70c8efe00ae4aa237e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26ed25f3feac102eae4ed421389c340f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2011-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_841e0bf057c5e368b07a3dcce8c6f455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60479d007e683fd9445dec2b9c7b53a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a342bd2c867a21b721c831bab08d38b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b736bce1b3a0f95be5da52663c7aefa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75ed6723d49a8c35b04c8d35194d0b26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a8ffdaffa088bcf96bba64a77fbeb8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb4e8b3bd9715849361c4dbff395d621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1994707ff753aefafce3d30dc3590d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b1a6e249c2c1b103da1e3f58f3b9a9c |
| publicationDate | 2015-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103156805-B |
| titleOfInvention | Ciprofloxacin thermo-sensitive type in-situ gel composition and preparing method thereof |
| abstract | The invention discloses ciprofloxacin thermo-sensitive type in-situ gel composition and belongs to the field of veterinary drug preparations. The thermo-sensitive type in-situ gel composition comprises, by weight volume (g/ml), 5%-10% of ciprofloxacin, 20%-26% of poloxamer 407, 0.5%-10% of poloxamer 188, 0.01%-0.04% of edetic acid, 0.009%-0.03% of bacteriostatic agent, and 0.1%-0.2% of antioxidant. Solvent of the composition is acetic acid - sodium acetate buffer solution. The invention further discloses a preparing method of the composition. The ciprofloxacin thermo-sensitive type in-situ gel composition is liquid at room temperature, jelling temperature is close to body temperature, and therefore dosing is convenient and jelling speed is high, jelling strength and adhering function are good, the dosing can be achieved with accurate positioning, and loss of drug is reduced. Furthermore, the ciprofloxacin thermo-sensitive type in-situ gel composition and the preparing method thereof have controlled-releasing and long-acting functions, dosage is low, the number of times of dosing is small, harm caused by implants normally used is avoided, and pain of patients is relieved. |
| priorityDate | 2011-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.