http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103145626-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 |
| filingDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f93c671a1c3c27961c714eb8f74946 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b30e91331472a3d06f994664f622216d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beedb3736b70358ec621a34819a04c4b |
| publicationDate | 2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103145626-B |
| titleOfInvention | Method for synthesizing 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde |
| abstract | The invention discloses a novel method for synthesizing 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde. The method comprises the following steps of: reacting sodium methoxide serving as alkali with methyl formate to generate3, 3-diethoxy-2-(hydroxymethylene) propionitrile sodium salt by taking diethoxypropionitrile/dimethoxy propanenitrile which is low in price and available as a raw material; and reacting the sodium salt which is not subjected to any treatment with S-methylisothiourea sulfate to directly obtain the 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde. Reaction conditions are moderate, unit operation is simple, and the total yield reaches 80-90%. According to the method, the raw materials are available and total cost is low, dangerous and toxic reagents are prevented from being used, a purification process is carried out only once in a synthesizing process, and industrial production is easy to realize. The method has the beneficial effects that the raw materials are low in cost and available, the total yield is high, the reaction is low in toxicity and the method belongs to green and economic synthesizing; and the experimental operation is simple, the reaction conditions are easy to control, an obtained product is easy to purify, and industrial production is easy to realize. |
| priorityDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.