http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103127053-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 |
| filingDate | 2011-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e50d71fd5bcafa2c4ec0bfceaffb09ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_388e2562d48d8a50331d530626fcbfe8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f526b9fcd0d3a1ef25dee444caaf275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa1ea209a75c3494fbc501a085c6b8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d755abca0daacdfe3e403658d8aff709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcf9ce9cab37e30a6c449fdce7711fa |
| publicationDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103127053-B |
| titleOfInvention | Medical application of 6-[2-(dimethylamino)ethoxy]flavone |
| abstract | The invention relates to the medicine technical field, and relates to 6-[2-(dimethylamino)ethoxy]flavone (a flavone compound WX-02) and its pharmaceutically acceptable salts, or its stereoisomers and prodrugs, and applications of its pharmaceutically compatibility-acceptable carriers or diluents in preparation of drugs for treating vascular smooth muscle spasm diseases, and applications as a calcium channel antagonist in treating cardiovascular diseases. In animal in-vitro experiments, WX-02 can dilatate vascular smooth muscles which are constricted by norepinephrine and potassium chloride. Additionally, preliminary research of WX-02 dilatation mechanism finds that WX-02 can inhibit intracellular calcium release and calcium influx caused by norepinephrine. Therefore, WX-02 can be used for preparation of drugs for treating vascular smooth muscle spasm diseases, and used as a calcium channel blocker. |
| priorityDate | 2011-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.