| abstract |
The present invention relates to a kind of new glucagon like peptide analogue and composition, can be used for raising mammiferous insulin expression and treatment diabetes.More specifically, described polypeptide derivative has at least one peptide simulation connexon, can provide long-acting effect, is used for the treatment of the adjoint gastrointestinal function of the diabetes disease relevant with other insulin secretion polypeptide, pancreas islet glucagon level and activity. |