http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103114108-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3d7e466c44c7b54e2a48e4bf62665ef |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
| filingDate | 2012-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91ed12155655f65526a545084993cb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4552bac46ade6bcbe49cd0d85a9ae299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bca0660d49f43ef4cb16e9376ce4133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41a439cbfb0f454bab06399f7665bef0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b030f170edd485c2f402233e425bb89 |
| publicationDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103114108-B |
| titleOfInvention | Method for preparing D-panthenol 16 ether monopalmitate by using lipase as catalyst |
| abstract | The invention relates to a method for preparing D-panthenol 16 ether monopalmitate by using lipase as a catalyst, belonging to the technical field of biological catalysis. The method comprises the following steps: by using hexamethylene as a reaction medium, carrying out enzymatic reaction on D-panthenol 16 ether and palmitinic acid by using lipase as a catalyst, wherein the conditions of the enzymatic reaction are as follows: the concentration of the substrate palmitinic acid is 50-200 g/L, the mol ratio of palmitinic acid to D-panthenol 16 ether (1.5-3):1, the mass ratio of palmitinic acid to lipase is 100:2-100:8, the enzymatic reaction temperature is 20-60 DEG C, and the reaction time is 12-24 hours; and after the enzymatic reaction finishes, filtering to recover the lipase, carrying out rotary evaporation under reduced pressure to remove the hexamethylene, and separating and purifying by column chromatography to obtain the D-panthenol 16 ether monopalmitate pure product, wherein the volume ratio of n-hexane:aether:acetic acid in the eluate is 89:10:1. The invention has the advantages of mild reaction conditions, favorable reaction selectivity, single reaction product and high conversion rate. |
| priorityDate | 2012-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.