http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103113594-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fb38ebd40c70e97cc5f1519c6699162 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00 |
| filingDate | 2013-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9da23f921b900219750d529308dad0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ee152722eb55313af5a41fe7f356270 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c601bb735b4170d60a73d5660ed02679 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09be8440e3d2c6835a19775721fc6e01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45c854c76930f3294eb6307a58bfbf6 |
| publicationDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103113594-B |
| titleOfInvention | Agarose-polymine-hyaluronic acid graft as well as preparation method and application of graft |
| abstract | The invention discloses an agarose-polymine-hyaluronic acid graft as well as a preparation method and an application of the graft. According to the invention, amine carboxyl and amine hydroxyl are connected via amido bonds by using soluble carbodiimide and carbonyl diimidazole; hyaluronic acid, polymine and agarose are grafted; the bioactivity and the targeting effect of the hyaluronic acid and the interaction property between capture genes and cells of the polymine are remained, and the gelling property of the agarose is acquired; the biodegradation characteristic is improved; and the acquired micro-particles have the targeting effect, is stable in body circulation, and is applicable to targeted drug control release carrier materials and tissue engineering scaffold materials. According to the invention, conditions for drug carriers to adequately release carried drugs in cells are created because the three polymers are connected via amido bonds and are easy to decompose in cells and a physiological environment. |
| priorityDate | 2013-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.