http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103113389-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d239abf2c2835d82b3aa0e0b5dfec593 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-16 |
| filingDate | 2011-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1991c09072a6e679dc334f581953a25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a828099cc309e93b709583794ed15257 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29497cd96440b2d4b697919a0fadfedc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_223a5629588ab362eb264ec0ffa96300 |
| publicationDate | 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103113389-A |
| titleOfInvention | Preparation method of sulbenicillin sodium |
| abstract | The invention provides a preparation method of sulbenicillin sodium. The preparation method comprises the following steps: condensing sulfophenylacetic acid and acyl chloride to generate mixed anhydride, condensing the mixed anhydride and protected 6-APA under an anhydrous condition, de-protecting to obtain sulbenicillin acid, reacting the obtained sulbenicillin acid with sodium isooctoate to obtain a salt, and crystallizing to obtain sulbenicillin sodium having a purity of above 99.2%. The preparation method has the advantages of simple operation, mild conditions, high yield, low cost and the like, and is suitable for the industrialized production; and the preparation method simultaneously allows the discharge amounts of three wastes to be substantially reduced and the environmental pollution to be small. |
| priorityDate | 2011-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.