http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103110932-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103110932-B |
| titleOfInvention | The novelty teabag of a kind of HIP-55 |
| abstract | The invention discloses the novelty teabag of a kind of HIP-55.HIP-55 albumen provided by the invention, HIP-55 protein coding gene or the recombinant vector containing HIP-55 protein coding gene or have following 1 containing the adenovirus of HIP-55 protein coding gene in preparation) or 2) application in the product of function: 1) suppress Proliferation of Cardiac Fibroblasts; 2) P38MAPK kinase activity is suppressed; The aminoacid sequence of described HIP-55 albumen is the sequence 2 in sequence table.Experiment of the present invention proves, the present invention finds that HIP-55 has expression in rat Different Organs, especially have high-caliber expression in heart, further isoproterenol (ISO) is induced, and in small rat Cardiac Fibroblasts, process LAN HIP-55 obviously suppresses Proliferation of Cardiac Fibroblasts; The activation of the P38MAPK that ISO can be suppressed to induce in process LAN HIP-55 cardiac fibroblast and kinase activity. |
| priorityDate | 2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 211.