abstract |
The present invention relates to spiral shell-Cycloamine derivative or its pharmacy acceptable salt, solvate or the hydrate of formula (I), or its one or more N-oxide compounds.Wherein R1; R2; R3; Q;-W-T-; R5; Z; With A, there is the definition provided in claims.Compound of the present invention has affinity to S1P acceptor and can be used for treating, alleviate or prevent wherein to relate to disease and the illness of S1P acceptor. |