| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f51223fc20c813701fb6eecbc23a9813 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495 |
| filingDate |
2013-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be35a040fcae38fa4480d9b3ae8b9d05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10154799fd50de60fd3640610ca6928f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea4586ec6e39ba16f3ab377c964d44e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_653eab7197c23b5165f72c8543d6ac32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3daea4e1874d9ab176a29761803f2da6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_166b3aafb8475a23c0f5ab10be0098d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dbc496566b13fbeb2dc5b1d3de56bf3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d43ad35c0a65ef99b41e509263a8d0d |
| publicationDate |
2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103087173-B |
| titleOfInvention |
Synthetic peptide vaccine of B cell epitope based on TGF(transforming growth factor)-beta1 and application thereof |
| abstract |
The invention discloses a synthetic peptide vaccine of B cell epitope based on TGF(transforming growth factor)-beta1 and application thereof, inhibits auxo-action of the cell factor TGF-B1-BB during the development process of liver fibrosis so as to inhibit the development of liver fibrosis to a some extent by constructing two epitope peptides of AY25 and LS30, coupling carrier proteins to synthesize an TGF-beta1 peptide vaccine, immunizing an ICR mice by intraperitoneal injection to induce the same to generate an anti-TGF-beta1 antibody, and neutralizing the cell factor TGF-B1-BB over expressed during CCL4 induced hepatic fibrosis process. |
| priorityDate |
2013-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |