http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103087077-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048 |
| filingDate | 2011-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103087077-B |
| titleOfInvention | Thienopyrimidine and furans miazines derivative, its preparation method and in application pharmaceutically |
| abstract | The invention discloses a kind of Thienopyrimidine and furans miazines derivative, its preparation method and in application pharmaceutically. Described derivative is the compound with general formula I, general formula I I, general formula III or general formula I V: . Thienopyrimidine provided by the invention and furans miazines derivative have obvious EGFR and suppress active, and part of compounds also has obvious inhibition activity to VEGFR, be expected to be developed as EGFR-TK EGFR or/and VEGFR inhibitor, for the preparation of the medicine of prevention or treatment and EGF-R ELISA EGFR and/or Angiogenesis factor receptors VEGFR relevant disease, for Development of Novel have low drug resistance maybe can alleviate early stage inhibitor drug resistance tyrosine kinase inhibitor drug provision new developmental direction and approach, have broad application prospects and medical value. |
| priorityDate | 2011-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.