http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103087013-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
filingDate 2011-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55858f6d28686cecffc556f8aced1198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d8df18bf02481943d5043b58a6216b6
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publicationDate 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103087013-B
titleOfInvention Paclitaxel preparation method
abstract The invention provides a paclitaxel preparation method, wherein a raw material 7-xylosyl-10-deacetyltaxol (10DAXT) is subjected to pretreatment conversion to obtain a paclitaxel mixture (the pretreatment steps comprise ozone oxidation, a C-7 site xylosyl removing reaction, a C-10 site acetyl introduction reaction, and the like), and the obtained paclitaxel mixture is subjected to column chromatography, recrystallization and other steps to obtain the paclitaxel pure product. With the method, the paclitaxel mixture derived from the 10DAXT can be effectively separated; and efficient, inexpensive and environmental protection paclitaxel preparation can be achieved, and an effective path suitable for industrial production is provided for complete yew resource utilization.
priorityDate 2011-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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