http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103083723-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fb38ebd40c70e97cc5f1519c6699162 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate | 2013-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fb6a85c234f6618c6330850ada8d159 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78b4106b5ca52220801ca39d657a860f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0db07f30118999b6e40e1dc791f90fdc |
| publicationDate | 2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103083723-B |
| titleOfInvention | Collagen/nano-crystalline cellulose skin regenerative material, preparation method and application thereof |
| abstract | The invention discloses a collagen/nano-crystalline cellulose skin regenerative material, as well as a preparation method and an application thereof. The skin regenerative material having excellent regeneration and repair effects can be obtained through the following steps of: taking collagen having excellent biocompatibility and degradability as a gene carrier material, and loading growth factors capable of expressing vascularization promotion on collagen microspheres by controlling the types and the loading capacity of the growth factors; compounding the microspheres with a collagen/nano-crystalline cellulose tissue engineering skin framework, and performing in-situ transfection on wound surface cells by using the growth factors, thereby realizing controllable sustaining secretion of angiogenesis promoting factors and promoting the vascularization of the skin regenerative material, and then the skin regenerative material having the excellent regeneration and repair effects can be obtained. The collagen/nano-crystalline cellulose skin regenerative material provided by the invention provides an excellent-performance skin substitute for treatment of deep skin defects such as wounds and burn, and chronic skin ulcers, and is capable of obviously promoting the healing of wound surfaces, reducing the hyperplasia of scars and relieving the pains of patients. The preparation method of the collagen/nano-crystalline cellulose skin regenerative material is simple, high in production efficiency, low in cost and suitable for industrial production. |
| priorityDate | 2013-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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