http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103073478-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-333 |
| filingDate | 2013-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_234231736cf75d06eacee10bb8c3f22f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2b974d42a7809274384547eaf00880b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e50cae8b3beb7f6308a33782a19d7d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f2b06c9271c3296151da376ef3d0743 |
| publicationDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103073478-B |
| titleOfInvention | Chemical synthetic method for pyrrole derivatives |
| abstract | The invention relates to a method for synthesizing 4-(formyl-5-hydroxymethyl-1 hydrogen-pyrrole-1-yl) butyric acid, and belongs to the field of organic synthesis. The conventional 4-(formyl-5-hydroxymethyl-1 hydrogen-pyrrole-1-yl) butyric acid can be synthesized by Maillard reaction of monosaccharide and gamma-aminobutyric acid under high pressure at high temperature, but the deficiencies of low yield, low purity, complex process, higher cost and the like exist. The method comprises the steps as follows: reacting 3-deoxyglucosone with gamma-aminobutyric acid, dehydrating to generate 4-(formyl-5-hydroxymethyl-1 hydrogen-pyrrole-1-yl) butyric acid, and purifying with a solid phase extraction method. The method is simple, the yield is increased, few byproducts are generated, and the purity is high. |
| priorityDate | 2013-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.