| abstract |
The invention discloses a method for preparing hydroxyl-substituted polycyclic aromatic compound. Dicarbonyl compounds such as intramolecular aldehyde ketone react with sulfohydrazide to obtain single N-sulfonyl-hydrazone, and the single N-sulfonyl-hydrazone reacts in an organic solvent under the alkaline condition, as a result, the hydroxy-substituted polycyclic aromatic compound is obtained. The method utilizes the activity difference between aldehyde and ketone, comprises a procedure of intramolecular carbon-carbon bond insertion-aromatization of the intermediate of the single N-sulfonyl-hydrazone, is short in reaction time and high in reaction yield, can well forbear and universally adapt to functional groups, and can be widely used for preparing various hydroxyl-substituted polycyclic armomatic compounds. |