http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103070855-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
filingDate | 2013-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103070855-B |
titleOfInvention | CR and 5,7-dihydroxy-4'-methoxy flavone are suppressing the purposes in telomere function |
abstract | The present invention relates to CR and the purposes of 5,7-dihydroxy-4 ˊ-methoxy flavone in suppression telomere function.Concrete, the invention provides 5,7-dihydroxyflavone and 5, the purposes of 7-dihydroxy-4 ˊ-methoxy flavone in preparation take telomere as target treatment tumor or anti-aging medicine, described is that target treatment tumor or anti-aging referring to cause the genomic instability that telomere damages, telomere loses function mediation with telomere.The present invention utilizes telomere position effect cell model to confirm, and above-mentioned two kinds of compounds can cause telomere damage, telomere loses function and genomic instability, specify that their value in tumor and aging-treatment and mechanism are that they have impact on the function of telomere, in view of the important target spot that telomere is defying age and antineoplaston, therefore the present invention has expanded 5,7-dihydroxyflavone and the scope of application of 5,7-dihydroxy-4 ˊ-methoxy flavone in clinical treatment. |
priorityDate | 2013-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.