http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103060278-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a2210b8e3d70cd3f4a886fdb4c56c86 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-135 |
| filingDate | 2012-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05e059a23ccc5de5009655da4f7935d6 |
| publicationDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103060278-B |
| titleOfInvention | Asia 1 type foot and mouth disease virus acid resistant mutant strains, capsid protein carried by same and encoding gene thereof and application |
| abstract | The invention discloses an Asia 1 type foot and mouth disease virus acid resistant mutant strains, capsid protein carried by same and encoding gene thereof and application. The invention includes obtaining Asia 1type foot and mouth disease virus P10 and P15 which are two generations of virus group with acid-resistant ability through acid stress screening and constructing and saving to obtain three Asia 1 type foot and mouth disease virus acid resistant mutant strains by using reverse genetics on the basis of analyzing the mutation sequence of the two generations of virus group. The amino acid sequence of the capsid protein carried by the Asia 1 type foot and mouth disease virus acid resistant mutant strain is respectively showed in SEQ ID No.2, SEQ ID No.4 or SEQ ID No.6. The problem of acid sensitivity of viral capsid during the process of producing and storing FDMV (foot and mouth virus) inactivated vaccine is solved and high quality seed virus is provided for preparing Asia 1 type FDMV inactivated vaccine. |
| priorityDate | 2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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