http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103059001-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abc0651c152f4827490aeed04f32cbe7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
| filingDate | 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f8f7b3825150caf76512cc2495692d |
| publicationDate | 2014-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103059001-B |
| titleOfInvention | Quinazolinone Schiff base containing triazole and preparation method thereof |
| abstract | The invention belongs to the technical field of drug synthesis, and specifically relates to a quinazolinone Schiff base containing triazole and a preparation method thereof. The chemical structure is 3-(4-((4-chloromethyl)-1H-1, 2, 3- triazole) benzal methylamino-2- methyl-7- fluorine-4 (3H)-quinazolinone. The preparation method comprises the following steps of: synthesizing the quinazolinone from 2- amino-4-fluorobenzoic acid, synthesizing triazole from 4-nitrobenzaldehyde, then, generating the 3-(4-((4-chloromethyl)-1H-1, 2, 3- triazole) benzal methylamino-2- methyl-7- fluorine-4 (3H)- quinazolinone by reaction between aldehyde and amine. The quinazolinone Schiff base compound containing 1, 2, 3-triazole synthesized by the method organically and orderly combines quinazolinone, triazole and triazole functional group and has very important application foreground in the fields such as biomedicine and medicine; in the method provided by the invention, the synthetic route is novel in conception, the raw materials are easy to get, operations are simple and cost is low, so that the method has good application foreground and is easy for industrial production. |
| priorityDate | 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.