http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103044437-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-09 |
| filingDate | 2012-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103044437-B |
| titleOfInvention | Be used for the treatment of the amphipathic conjugate nano particle of tumour and preparation method, application |
| abstract | The present invention relates to biomedicine technical field, particularly a kind of be used for the treatment of tumour amphipathic conjugate nano particle and preparation method, application.The amphipathic conjugate nano particle being used for the treatment of tumour of the present invention, comprises by the amphipathic conjugate of the hydrophilic anti-tumor medicine esterification of carboxylic hydrophobic anticancer drug and hydroxyl.Compared with prior art, amphipathic conjugate of the present invention self-assembly can form nano particle in water, without the need to any drug conveying carrier, this conjugate self just can realize drug conveying, strengthened and retention effect by the permeability of tumor tissues, this conjugate nano particle more effectively can enter tumour cell, reduces Normocellular toxic side effect; After conjugate nano particle enters tumour cell, two kinds of antitumor drugs can be discharged through ester bond degraded, reach the object of two kinds of medicine Synergistic treatment cancers. |
| priorityDate | 2012-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.