| abstract |
The present invention relates to doped with Fe 2+ Ion and Fe 3+ The hydroxyapatite of ion, described Fe 2+ Ion and Fe 3+ Calcium ion in ionic portions ground replacement lattice.Described hydroxyapatite is characterised by, by applying the intrinsic magnetic of 0.05 to the 8emu/g of the magnetic-field measurement of 34Oe, this is owing to there is magnetic Nano farmland in the lattice of HA, it is contemplated that there is the limited amount second magnetic phase of less than about 3 volume %.Described intrinsic magnetic hydroxylapatite can carry the biological substance in following: protein, gene, stem cell, somatomedin, angiogenesis factor, active substance and medicine, under the control of outside magnetic field, as biological substance or the carrier of medicine and releasing agent, as the contrast agent in diagnosis or for bone or bone regenerating bone or cartilage. |