http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103028351-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2c55a9de09e08e3404c0a5a1ae4dc7
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01G49-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F1-11
filingDate 2012-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54ffb74ea86bccc06b3ef924c3b73974
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59edc902c3dd81a5ad9879b310aef433
publicationDate 2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103028351-B
titleOfInvention Benzene sulfonic acid modified magnetic microsphere and preparation method and application thereof
abstract The invention discloses a benzene sulfonic acid modified magnetic microsphere and a preparation method and an application thereof. The preparation method comprises the following steps: firstly compositing ferroferric oxide magnetic microsphere, then adding excessive stronger ammonia water and tetraethoxy-silicane, making the tetraethoxy-silicane hydrolyze and polymerize on the surface of magnetic microsphere to obtain a Fe3O4/SiO2 magnetic material, finally adding excessive dichloromethane solution of 2-(4-chloride sulfonyl phenyl)-ethyl trimethoxy silane and carrying out silanization reaction to obtain the magnetic microsphere with surface modification of benzene sulfonic acid. The preparation method in the technical scheme of the invention has the advantages of simple, effective and good reproducibility, and the obtained magnetic microsphere has a uniform grain size, bigger surface area and controllable size, can realize fast separation of solid phase and liquid phase by using simple external magnetic field effect in the solution, and can adsorb alkaline compound from the complex substrate under the strong electrostatic interaction of the sulfonic acid group and the hydrophobic interaction of the benzene ring.
priorityDate 2012-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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