http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012771-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-10 |
filingDate | 2012-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103012771-B |
titleOfInvention | Acid-sensitive splitting-decomposable connecting unit and application thereof |
abstract | The invention discloses an acid-sensitive splitting-decomposable connecting unit and application thereof. The acid-sensitive splitting-decomposable connecting unit has a structural formula described in the specification, wherein m is 1 or 2, n is any one integer between 0 and 44, X is Br, NH2, N3 or OH, and Y is Br, NH2, N3 or OH. The acid-sensitive splitting-decomposable connecting unit can realize effective splitting decomposition under an acid condition, and can be efficiently connected with a hydrophilic compound and a hydrophobic compound to obtain an amphiphilic block copolymer; and an amphiphilic block copolymer self-assembly micelle can be used as a drug transport agent. Compared with the prior art, the acid-sensitive splitting-decomposable connecting unit has the advantages that required raw materials are simply and easily available, synthesis processes are conventional chemical reactions, and reaction conditions are mild; and a large quantity of acid-sensitive splitting-decomposable connecting units are easily synthesized. |
priorityDate | 2012-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.