http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012672-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_896b11ed232c0d8e29f572d158bbd22f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2012-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a532927f4aba4311aa4a5edf5096391d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_920946659ac92544bbb654a4c9b7647d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1049cc7b6195adc63cd913a534a3cde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3a8d89db2cee9d42334329a5191812c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78c3eca706f5e62cd545f09c48423c0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d234c563be44ad5e830c5f4d9aa251f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81d898fbd21d42e2821300f85e1f18c8 |
| publicationDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103012672-B |
| titleOfInvention | 5-fluorouracil copolymer with anti-tumor activity and preparation method of 5-fluorouracil copolymer |
| abstract | The invention provides a 5-fluorouracil copolymer with anti-tumor activity. 5-fluorouracil or 5-fluorouracil and sulfadiazine is or are connected to N-(2-hydroxypropyl) methacrylamide through a polymerization mode to form a macromolecule copolymer with good biological compatibility. The macromolecule copolymer is used for connecting the 5-fluorouracil with anti-tumor activity and the sulfadiazine to a tumor targeted drug carrier N-(2-hydroxypropyl) methacrylamide to ensure that the anti-tumor activity is overlapped, further the inhibition of the macromolecule polymer to tumors is promoted, and the standing time of anti-tumor drugs in tumors is greatly prolonged; and meanwhile, by adopting the macromolecule carrier HPMA (hydroxypropyl methacrylate), the toxicity of the anti-cancer drugs is reduced, the hurt to normal tissues is decreased, and a new idea is provided for preparing novel anti-tumor drugs. |
| priorityDate | 2012-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.