http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012425-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00 |
filingDate | 2013-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103012425-B |
titleOfInvention | Benzofuran compound, and preparation method and application thereof |
abstract | The invention discloses benzofuran compound, and a preparation method and application thereof. The structural formula of the benzofuran compound is shown in the specification, wherein R is -OH; the molecular formula is C19H16O3; the compound is named gramniphenolF; R is -OMe; the molecular formula is C20H18O3; and the compound is named gramniphenolG. According to the preparation method, dried bamboo orchid branch, leaf and/or fruit are subjected to extractum extracting, organic solvent extracting, silica gelcolumn chromatography and high pressure liquid chromatography separation. The benzofuran compound can be applied to preparation of a drug for resisting tobacco mosaic virus. The inhibition ratios of the gramniphenolF and the gramniphenolG respectively reach 35.8+/-3.6% and 32.1+/-3.8% by an experiment of resistance to tobacco mosaic virus; the benzofuran compound has good activity of resisting the tobacco mosaic virus, and the inhibition ratio is higher than the inhibition ratio (31.8+/-2.5%) of a positive contrast Nanning mycin. The compound disclosed by the invention is simple in structure and good in single activity, can be used as a lead compound of the drug for resisting the tobacco mosaic virus, and has good application prospect. |
priorityDate | 2013-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.