http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012268-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7daba9f88bf72280b96e882c46896c55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
| filingDate | 2013-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8ae3668ac0ac96e507e4ee550cf9d6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23f31bdf5b3ec4985d9fecb596f782ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06087aee9a431799f4d1a68b16950d61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d37acf46a3ab7ae96d4ca71b57470016 |
| publicationDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103012268-B |
| titleOfInvention | Novel preparation method for ivabradine |
| abstract | The invention belongs to the field of pharmaceutical chemical engineering, and relates to a novel synthesis method for ivabradine. The novel synthesis method for ivabradine comprises the following steps of: reacting a compound III with a compound IV in a reaction solvent under the catalysis of an alkali, performing post-treatment to obtain a compound II, and performing hydrogenation reaction under a system containing a catalyst and ammonium formate to obtain a compound I, namely, ivabradine. The method is short in synthesis route, simple to operate, greatly lowered in the difficulty of synthesis for ivabradine, low in cost and high in product yield; and most importantly, the method is good in safety, not involved with high-pressure hydrogenation, free from the use of an inflammable gas, namely, hydrogen, and great in industrialization base and application value. |
| priorityDate | 2013-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.