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filingDate 2012-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe5c256a65c25821bd336571e8506a66
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publicationDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103007347-B
titleOfInvention Method for loading gentamicin by using TiO2 nanotube coating in situ synthesized on Ti surface
abstract The invention relates to a method for loading gentamicin by using a TiO2 nanotube coating in situ synthesized on the Ti surface. The method comprises the following steps of: firstly, preparing a TiO2 nanotube coating on a preprocessed Ti substrate by using an anodic oxidation method; secondly, immersing the prepared TiO2 nanotube into an alkali solution; and thirdly, loading the gentamicin in the TiO2 nanotube coating by using a coprecipitation method. Compared with the prior art, the invention provides a preparation path of the TiO2 nanotube coating, which is simple in process and favorable in biocompatibility, and a mode for medicine loading/releasing by using the TiO2 nanotube, as well as a novel method for prevention and treatment of prosthesis-related infections after artificial joint replacement.
priorityDate 2012-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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