http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103006741-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41d42dda56335b56f7f1545dcbc7ca22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-31 |
| filingDate | 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f670a406e9213be63f04d83c5ce563dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13e328d32cb06a053728539987a2e84a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b048d99e6a21753c00206ca001dc4202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd3c1f0259496e1847caed931931a850 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3e37f3786a3b0084afba30ac0047f46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5fc23723bcd5643cc16de64ae0a74cc |
| publicationDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103006741-B |
| titleOfInvention | Semen lepidii anti-tumor effective component extract, as well as preparation method and application thereof |
| abstract | The invention discloses a semen lepidii anti-tumor effective component, a preparation method of the semen lepidii anti-tumor effective component and an application of the semen lepidii anti-tumor effective component in the field of anti-tumor. The preparation method comprises the following steps of: extracting semen lepidii (roasted) with water; and extracting with ethyl acetate and water saturated n-butyl alcohol sequentially; collecting water saturated n-butyl alcohol extract; separating with a silica (200 to 300 meshes) column; and performing gradient elution with dichloromethane-methanol in different proportions, wherein the dichloromethane-methanol (5:1) elution part is a semen lepidii anti-tumor effective part. The part has a remarkable effect of inhibiting U251 (glioma cell line), HepG2 (human hepatoma cell line), SGC (human gastric carcinoma cell), mcf-7 (human breast cancer cell) and SCLC (lung carcinoma cell), and can be used for preparing an anti-tumor medicament. |
| priorityDate | 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.