| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2011-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d40fc0ef32fd7ba7716e0e50c027daa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44cca8f9ad502ae8cdf13fe19c16cb09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a88cd15ce0c5dc42ef29dc5e5b40ee0 |
| publicationDate |
2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103002919-B |
| titleOfInvention |
Tumor-targeted delivery of immunomodulators by nanopolymers |
| abstract |
Nanoconstructs and methods of using the nanoconstructs are described having three components: (1) biodegradable nanopolymers and nanoparticles; (2) immunopharmaceuticals, such as CpG; and (3) tumor A binding device that actively targets tumor cells, such as melanoma cells, by receptor-mediated uptake. Antitumor immunity was further enhanced by combining PG-CpG nanoconstructs with agonists of positive costimulatory signals and inhibitors of negative immune regulatory signals. |
| priorityDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |