| abstract |
The present invention provides C-3 substituted -9-deoxy-9A-aza-9A-homoerythromycin A derivatives, which have the structure shown in general formula (I), wherein R is H, hydroxyl or Methoxy; R2 is hydroxyl; R3 is an organic substance substituted or unsubstituted by a heteroatom, and the heteroatom is one or more of halogen, N, O and S; R4 is H, benzyloxy Carbonyl, benzoyl or acetyl. The compound of general formula (I) in the present invention is an antibacterial agent, which can be used to treat various bacterial and protozoan infections. The present invention also relates to the application of the compound, its preparation method and the composition formed by the compound. |