http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102977089-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9d77c2320308698bbf72fdec0ed40d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ea6af237c451ba39f93109f83a3c4d8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc45545f0193b54aab24d76427bc8f5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a129620563192d4b83beea4382b1eb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b82fd229a2fce66081dbcf653af2c14e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b501874e70e6a632207a173934a09ff0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_224f9670975c166a17491d66709197af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66f017af3de2dd84cbea89c142d9be88 |
| publicationDate | 2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102977089-B |
| titleOfInvention | Method for preparing high-purity cefdinir antibiotic 7-side chain synthesis critical material |
| abstract | The invention discloses a method for preparing a high-purity cefdinir antibiotic 7-side chain synthesis critical material. The method comprises the following steps of: by taking demethylated ethyl 2--2-methoxyiminoacetate and triphenylcarbinol as raw materials, taking a carbonic ester solvent as a solvent, taking a dimethyl carbonate boron trifluoride solid complex as a catalyst, preparing (Z)-2-(2-amino-4-thiazolyl)-2-benzyltrimethylimineethyl acetate; adding an inorganic alkali solution into an alcohol solvent to carry out a hydrolysis reaction, acidizing the solution by utilizing inorganic acid after the hydrolysis reaction is finished, and preparing (Z)-2-(2-amino-4-thiazolyl)-2-benzyltrimethylimineacetic acid; by taking the (Z)-2-(2-amino-4-thiazolyl)-2-benzyltrimethylimineacetic acid and DM as raw materials and a pyridines compound as a catalyst in a halogenated alkane solvent, dripping mixed solution of triethyl phosphate and triethylamine, and preparing the MEAT. The reaction process is easy to operate, and the used solvent is low in toxicity, environment-friendly, easy to recycle, high in yield, low in cost and suitable for industrialization. |
| priorityDate | 2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.