| abstract |
The present invention relates to quinoline derivatives represented by general formula I and their pharmaceutically acceptable salts, hydrates or prodrugs, wherein the substituents M, R 1 , R 2 , X, Y and n have the meaning out. The present invention also relates to the compound of general formula I having the effect of inhibiting c-Met kinase, and also relates to the preparation and treatment of diseases caused by abnormally high expression of c-Met kinase by such compound and its pharmaceutically acceptable salt and hydrate Use in medicine, especially in the preparation of medicines for treating and/or preventing cancer. |