http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102967675-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_427200152b8a3acbbfeb8b4106e031b1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2012-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce2b840dfed2705382c30cb528a98ba5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a8e3d0df3c7ae88dfb9994037c8a136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bc45a9a8077790030fcde33676f31aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ecfeb00e878c4b468acccf55cc4a6f0 |
publicationDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102967675-B |
titleOfInvention | Capillary electrochromatography determination method suitable for separation of nicotine and metabolite thereof |
abstract | The invention relates to a capillary electrochromatography determination method suitable for the separation of nicotine and a metabolite thereof. The capillary electrochromatography determination method comprises a capillary silica-gel functional column used for capillary electrochromatography separation determination. The capillary electrochromatography determination method is characterized in that the capillary silica-gel functional column is a processed specific capillary silica-gel functional column; the specific capillary silica-gel functional column comprises any one of a hybrid silica-gel capillary column modified by betaine and an end group end-capping octadecylsilane bonded silica-gel capillary column or a polyhedral silsesquioxane methacrylic acid-hydroxyethyl methylacrylate copolymerization column; negative-charge high voltages and liquid-phase pump auxiliary pressure are applied on the tail end and the sampling end of the capillary silica-gel functional column, and the continuous separation of the nicotine and the metabolite thereof is realized under the dual action of electrophoretic separation and capillary liquid-phase chromatography separation. The capillary electrochromatography determination method disclosed by the invention can be used for separating the object to be determined by comprehensively applying electrophoresis and chromatography modes, thereby greatly increasing the chromatographic elution efficiency and separation column efficiency of the nicotine and the metabolite thereof. |
priorityDate | 2012-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.